Rituximab in Membranous Nephropathy: Not All Studies Are Created Equal

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Rituximab in Membranous Nephropathy: Not All Studies Are Created Equal.

Many prospective studies and a recent randomized controlled trial have shown that the B-cell-depleting monoclonal antibody, rituximab, safely promotes the remission of nephrotic syndrome in approximately 65% of patients with membranous nephropathy (MN). Mechanistic studies have indicated that rituximab-induced proteinuria reduction is associated with clearance of anti-podocyte antigens phosphol...

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Rituximab in Membranous Nephropathy: Not All Studies Are Created Equal

Many prospective studies and a recent randomized controlled trial have shown that the B-cell-depleting monoclonal antibody, rituximab, safely promotes the remission of nephrotic syndrome in approximately 65% of patients with membranous nephropathy (MN). Mechanistic studies have indicated that rituximab-induced proteinuria reduction is associated with clearance of anti-podocyte antigens phosphol...

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ژورنال

عنوان ژورنال: Nephron

سال: 2016

ISSN: 1660-8151,2235-3186

DOI: 10.1159/000450659